Effect of dextran sulphates on thrombin activity.
نویسندگان
چکیده
منابع مشابه
Effect of dextran sulphates on thrombin activity.
To clarify the action of dextran sulphate, a heparin analogue, in the clotting of fibrinogen by thrombin, determinations were carried out on the clotting activity, the release of fibrinopeptides from fibrinogen, and the hydrolytic activity of thrombin against a peptide chromogenic substrate in the absence or presence of antithrombin III (heparin cofactor). It was shown that dextran sulphate its...
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15 صفحه اولThe estimation and recovery of dextran sulphates in biological fluids.
The dextran sulphates resemble heparin in being active inhibitors of several different forms of biological activity, e.g., blood coagulation, serum complement activity, and certain enzyme systems (Walton, 1954). In each case the activity of the dextran sulphate appears to be dependent upon direct interaction with one or more protein components of the biological system under investigation. In fa...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1979
ISSN: 0021-9746
DOI: 10.1136/jcp.32.5.439